Post-Frey recovery · 🆕 Turkey Tail live ~8/11 · NAC final step 8/14
spermidine-miricell) was minutes old, asserted from a vendor page and falsified by a photograph of the bottle.8/11 ✓
🔴 THIS REV (7.85 → 7.86, 10/29) — THE MORNING COFFEE AND ITS 200 mg THEANINE MOVE 9:00 → 8:30 · L-GLUTAMINE STAYS AT 15 g AND TAKES THE FIRST BITES · DAY TOTALS UNCHANGED. His questions, 10/29: is 9:00 clearly better for the coffee than 8:30, which suits him more naturally; is glutamine better just before eating or just after; and is 5 g three times a day still right — assessed anew. His calls: 8:30, with 9:00 on a sleep-in morning; keep 15 g and retire the 15 → 5 g step-down; noon and dinner glutamine at the first bites, from now. Why 8:30 is fine: 9:00 was iron geometry, and iron exited 9/23; the theanine pairing that kept it there moves with the cup. Modelled, it’s a wash — theanine at the caffeine peak +10%, 10:00–11:15 about 20% thinner — so his preference decides. Why 15 g: both trials that exist used exactly 15 g/day (Zhou 2019, USA; Rastgoo 2021, Iran — each against whey protein); raised gut permeability has been measured in chronic pancreatitis, though never in him; nothing supports 5 g. Safety, calibrated: Norway’s VKM judged up to 16.5 g/day unlikely to cause harm in adults — he is at half its per-kg benchmark — but asks for safety studies in diabetics (he has T3c), and the 9/22 ALP is an open flag. First bites: before the meal rather than after — mechanism, not evidence — and not with the DAO sip. One ⟨C⟩ candidate filed, unruled. Every daily total unchanged. Closes items 86 and 101, and 87 twice as a gate — a numbering collision. Supersedes 7.85 — delete that zip. PRIOR REV, kept as history: 7.84 → 7.85, 10/24 — ONE NAC CAPSULE MOVES TO 6:00 AM FROM SAT 11/7 · DAY TOTAL UNCHANGED. His decision, 10/24: one NAC to the morning, for coverage during the morning Adderall hours; which one, he handed to Claude on the condition that GlyNAC is unharmed. The call: one NOW 600 from the 8 PM dessert, not one of noon’s two — the same morning gain (about +40%, 6:30 AM to noon, on a one-compartment proxy), more afternoon instead of less, and a third off the bedtime dose while off the PPI. GlyNAC is unaffected: no GlyNAC trial ties benefit to an evening dose — Lizzo 2022 split its doses morning and evening; his noon, 3 PM and dinner glycine pairs are untouched; the overnight window was Claude’s idea, struck 8/3. Gates: the enzyme watch over; seven clean mornings (in hand 10/24); buspirone settled. After the draw on a homocysteine-draw morning. Watch: 11/7–11/11 — any stomach signal sends it back to 8 PM. Next starts: grape seed and DAO not before Thu 11/12, one at a time. Records: Kumar 2023’s methods give no timing, and its dose sentence reads two ways — recorded as unsettled; glynac-1to1-ratio stands. Four “no indication on file” lines noted as overtaken by item 37 on 8/14. Every daily total unchanged. Opens item 143. Supersedes 7.84 — delete that zip. PRIOR REV, kept as history: 7.83 → 7.84, 10/23 — THE DIGESTIVE ENZYMES GO LIVE: DIGEST BASIC, ONE PER MEAL, FROM DINNER 10/23 · RE-FILED AS A FUNCTION MATCH, NOT LIKE-FOR-LIKE. The 7.82 → 7.83 summary and everything earlier now live only in the rev history inside master-regimen.md.
cordyceps-antiplatelet entry. rev 7.51 is superseded — delete it. Changed at rev 7.51 — Cordyceps dose closed on a bottle read: Real Mushrooms 500 mg × 2 = 1,000 mg/day ⟨N✓8-24⟩ · DEVICES card added (Truvaga Plus). rev 7.50 is superseded — delete it. Changed at rev 7.50 — the first SCHEDULE rev since 7.46: Taurine 500 mg added at 4:00 PM ⟨N 8-24⟩ (day total 4,000 → 4,500, six slots, stated indication: smooths the 4 PM Adderall IR) · Cordyceps STARTED 8/24 ⟨N✓⟩ — Real Mushrooms CORDYCEPS-M, C. militaris, 500 mg × 2 = 1,000 mg/day, 8% β-glucans · Mastic swap LIVE — NutriCology, NOT Greco Gum ⟨N✓8-24 label read⟩, CGN retired, oat fiber gone, supplemental calcium → 0 · Truvaga Plus recorded LIVE since ~8/13 · gabapentin nighttime split DECLINED ⟨N 8-24⟩ · IV-iron route moved to Kuhlman, appointment 8/25 · the "~8/21" draw date de-anchored — it never happened. 🩸 Changed at rev 7.47 — IRON 36 mg elemental added (2 × 18 mg ferrous bisglycinate, alternate days, 6:00 AM fasted) on the 8/10 results: ferritin 10, iron saturation 4%, CRP 2. CRP normal means no acute-phase inflation — ferritin 10 reads at face value. Green tea / maté moved 7:00 → 8:00 AM, then → 9:00 AM ⟨N 8-26⟩ to clear the iron dose; that reverts on iron's exit, not gabapentin's. Ganzoni deficit ~1,272 mg — oral closes it in months, so the IV route CLOSED 8/27 — ordered by Kuhlman, ferric derisomaltose (Monoferric), avoiding FCM. Open items 3, 21, 40, 46 and 53 closed on results. Changed at rev 7.46 — ⚕ GABAPENTIN 1,200 mg/day added (600 mg at 4:00 PM + 8:45 PM) for restless legs, as a bridge while iron studies are pending. Both evening magnesium doses moved to the 6:30 PM dinner to clear its LAT1 absorption window — this reverts when gabapentin exits. Adderall XR-2 moved 11:55 → 11:15 AM, and back to 11:55 at rev 7.55 ⟨N 8-26⟩. NaturDAO → Seeking Health DAO Enzyme at −15 min (11:45 · 2:45 · 6:15). Resveratrol CUT — executes after the ~8/21 draw, not today. Quercetin's first dose line (~100 mg actual, not the 400 a prior session recorded). Changed at rev 7.40 — Glycine corrected to 8,235 (the Mg bisglycinate's own 1,235 mg was never counted — accounting, not intake), Taurine 8:45 PM restored to 1,000 → day total 4,000, bottle check closed. Changed at rev 7.39 — Mastic Gum → Greco Gum (ordered 8/11, CGN until it lands), cardiometabolic indication on file, oat fiber and its ~38 mg Ca leaving with the swap. Changed at rev 7.38 — NAC to 3,800, Turkey Tail live, Grape Seed cut. Changed at rev 7.35 — Taurine redistributed: six slots → five, three now pre-meal, total unchanged at 3,500. Changed at rev 7.34 — Saffron, R-ALA, Panax, Bilberry and MegaSpore now live · Agmatine ×4 and Gymnema return 8/7 · L-Theanine 1,500 across 10 doses.DAO (diamine oxidase) is the histamine-degrading enzyme. Its cofactors are copper · calcium · topaquinone (TPQ) — not B6. Ranked for this phenotype, the real levers are:
1. Substrate competition — 🔵 Reopens 8/7: agmatine returns at 1 g/day, the largest DAO-substrate load in the stack — and the Spermidine collision at Meal 1 goes live with it, which is why no agmatine dose lands at noon — 🆕 moot from 10/10: spermidine exited. Until then the supplemental load is zero. The premise was in-vitro/porcine and is an order-of-magnitude flag, not a measurement. · 2. Mucosal integrity — DAO is made by gut-lining cells; post-Frey + ulcers + EPI is the likely suppressor. Intervention already live: L-Glutamine 15 g/day. · 3. Copper — the actual metal cofactor, now added to the 8/1 draw.
⚠ B6 is not a DAO lever — it's upstream on histamine synthesis (histidine decarboxylase). 🆕 HISTORICAL ⟨8-15⟩ — NaturDAO left the regimen 8/15, replaced by Seeking Health DAO Enzyme (DAOgest® porcine, 30,000 HDU, bottle-confirmed). Retained because it still applies to any legume-DAO product: do not switch to NaturDAO Plus — it bundles P5P on the same retired rationale.
Acetaminophen — documented adverse, VM July 2026 · NSAIDs — ulcer / GI-bleed history · Potassium supplements — on the ARB
⚠ Soy has moved out of this tier at rev 7.25 — it is now activity-gated, not categorical. See below.
Exclude: raw / unheated / high-TIA soy — raw soy flour, raw soybeans, unheated soy protein powders. · Cleared: soy lecithin · soybean oil · fermented soy · hydrolysed soy protein / soy peptone · a declared trace from a fermentation medium. SerinAid PS sits here — not as an exception, as the general case. Erinamax, the other example, left the regimen ~9/8. 🆕 NaturDAO left the regimen 8/15 — see the yardstick note.
Ceiling of the effect. Kunitz and Bowman-Birk are serine-protease inhibitors — trypsin and chymotrypsin only. Not lipase. Not amylase. Creon is dosed in USP lipase units and titrated on fat absorption. "Soy stops Creon working" overstates the ceiling by the whole therapy and is retired.
Why a constraint survives at all — and it is not enzyme inactivation: a large active STI load removes luminal-protease feedback and raises CCK → pancreatic stimulation. Wrong direction for a post-Frey pancreas. Requires raw-flour-scale exposure.
Yardstick — 🔴 NOW HISTORICAL ⟨C·8-15⟩: NaturDAO ~96 mg/day legume protein was cleared. That product left the regimen 8/15 and its porcine replacement carries ZERO legume protein — the number survives as the highest legume exposure this regimen has cleared in practice, but it is no longer a live intake. Erinamax ≈5 µg/day upper bound = ~19,000× below that — historical too, since Erinamax left ~9/8.
🏷 Provenance ⟨?⟩ — untagged in every rev, no source anywhere in the document, no soy interaction on the Creon FDA label, and none of the cited literature touches PERT, EPI or fat absorption. It was the only Standing Constraint that explained itself instead of citing something. Origin unrecalled — not assumed in either direction.
Dark or tarry stool · visible blood · new dizziness · resting HR climbing · fever or rigors · any BP reading ≥180/120 → urgent care, not a message
The regimen produces atypically suppressed inflammatory markers (WBC, CRP). Clinical suspicion outweighs standard lab thresholds when assessing acute infection, cholangitis, or pancreatitis flare. A normal white count does not exclude infection in this patient.
Adversarial passes have lodged zero findings against the chronic core. Not one of the ~40 compounds was faulted on evidence quality, dose, timing, interaction, or sourcing — outside the post-surgical window. What gets corrected are the overlays, the instruments, and the reasoning — all of which sit around the regimen, not in it. This rev is one more of those: a stated rationale was wrong; the compound stayed.
The record: GMI 5.7–5.8% across 180 days · zero readings above 250 · eGFR 112 · normal hepatic function despite an obstruction history · HbA1c 6.1% in T3c diabetes, without insulin. 🆕 Dated — 9/30: the 8/10–9/8 Clarity window read GMI 6.3%, the clean A1c on file is 6.2% (6/11), and ALP has sat just above range on all three 2026 draws with normal bilirubin and transaminases.